MSG has been consumed by communities as a flavor enhancer. MSG has proofed increasing ROS and in the same time decrease sperm quality. Gitclnrin C (VC) refer to nonenzymatic radical scavengers preventing cells to oxidative stressed. Unfortunately the role of VC to increase sperm quality in MSG exposure still unclear Aim: of the present study is to reveal whether treatment of VC will able to enhance sperm quality which is indicated by elevation of TDT, concentration, motility and vitality of sperms. Method: In the Post Test Only Control Group Design, 25 male of three month-old Wistar rats with + 200 grain body weight randomly assigned into 5 groups, each group consist of 5 rats. A week after rats acclimatization in the colonies cage, the treatment was given during 30 days successively. At the final of treatment 2 cm ductus deference from cauda epidemic to ampulla ductus deferens was taken and collected in; rsiologvs salt. Further more concentration, motility and vitality were tested according to WHO standard procedure. On the other hand TUT will he tested by tissue testes preparation. Result: Manova statistical analysis indicate the significantly difference (p=0.000) among 5 groups. Uni variate statistical analysis show that TDT motility and vitality in A group (aquades) Deere significantly higher (p=0.000) compare to B group (MSG) C, D, and E groups (VC+MSG). In C, D, and E group, TD7; motility, and vitality were higher significantly (p=0.000) compare to B group, but lower significantly (p=0.000) compare to 4 group. In D group, TDT, motility, and vitality were higher significantly (p=0.000) compare to C and B groups, although loiter significantly (p=0.000) compare to A group. In Egroup TDT, motility, and vitality were higher significantly (p=0.000) compare to B. C and D groups, eventhough lower significantly (p=0.000) compare toAgroup. In Cgroup, concentration was higher significantly (p=0.000) compare to B group, nothing difference (p=0.616) compare to A group, lower significantly (p==0.000) compare to I) and E groups. In 1) group concentration was higher signifcantly (p-=0.000) compare to A and B groups, lower significantly (p=0.000) compare to E group. In group E concentration was higher significantly (p=0.000) compare to A group. Consistent with discriminant analysis TDT, concentration, and motility were constitute of discriminant variable among four dependent variables. The present result suggest that TDT, concentration, and motility variables have

        Kata kunci: MSG; Concentration; Motility italitr; Sperm quality